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Date Updated: October 18, 2017

Comprehensive Basic Science Examination

The Comprehensive Basic Science Examination content outline includes:

Outline
Systems
General Principles of Foundational Science
15%–20%
  Biochemistry and molecular biology
  Biology of cells
  Human development and genetics
  Biology of tissue response to disease
  Pharmacodynamic and pharmacokinetic processes
  Microbial biology
  Normal age-related findings and care of the well patient
Immune System
1%–5%
Blood & Lymphoreticular System
5%–10%
Behavioral Health
1%–5%
Nervous System & Special Senses
5%–10%
Skin & Subcutaneous Tissue
1%–5%
Musculoskeletal System
5%–10%
Cardiovascular System
5%–10%
Respiratory System
5%–10%
Gastrointestinal System
5%–10%
Renal & Urinary System
5%–10%
Pregnancy, Childbirth, & the Puerperium
1%–5%
Female Reproductive System & Breast
1%–5%
Male Reproductive System
1%–5%
Endocrine System
5%–10%
Multisystem Processes & Disorders
5%–10%
Biostatistics, Epidemiology/Population Health, & Interpretation of the Medical Lit.
5%–10%
Social Sciences, Including Communication, Medical Ethics, and Death & Dying
1%–5%
Physician Task  
Applying Foundational Science Concepts
50%–60%
Diagnosis: Knowledge Pertaining to History, Exam, Diagnostic Studies, & Patient Outcomes
20%–30%
Pharmacotherapy, Intervention & Management
5%–15%
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