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Date Updated: July 3, 2018

Clinical Science: Medicine

The Clinical Science Medicine content outline includes:

Outline
System  
General Principles, Including Normal Age-Related Findings and Care of the Well Patient 1%–5%
Immune System 1%–5%
Blood & Lymphoreticular System 5%–10%
Nervous System & Special Senses 5%–10%
Skin & Subcutaneous Tissue 5%–10%
Musculoskeletal System 5%–10%
Cardiovascular System 10%–15%
Respiratory System 10%–15%
Gastrointestinal System 8%–12%
Renal & Urinary System 8%–12%
Female Reproductive System & Breast 1%–5%
Male Reproductive System 1%–5%
Endocrine System 5%–10%
Multisystem Processes & Disorders 3%–7%
Biostatistics, Epidemiology/Population Health, & Interpretation of the Medical Lit. 1%–5%
Social Sciences, Including Medical Ethics and Jurisprudence 1%–5%
Physician Task  
Applying Foundational Science Concepts 10%–15%
Diagnosis: Knowledge Pertaining to History, Exam, Diagnostic Studies, & Patient Outcomes 50%–55%
Health Maintenance, Pharmacotherapy, Intervention & Management 30%–35%
Site of Care  
Ambulatory 55%–65%
Emergency Department 20%–25%
Inpatient 15%–20%
Patient Age  
17 to 65 70%–80%
66 and older 20%–30%

Please note that beginning in August 2018, NBME will add short-answer questions to the Medicine clinical science subject examination administered at both medical schools and Prometric test centers. Read announcement

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