Showing 1 - 3 of 3 Research Library Publications

Awareness of Diagnosis Predicts Changes in Quality of Life in Individuals with Mild Cognitive Impairment and Mild Stage Dementia

Posted: | Shana D. Stites, Jonathan D. Rubright, Kristin Harkins, Jason Karlawish

International Journal of Geriatric Psychiatry: Volume 38 - Issue 6, e5939

 

This observational study examined how awareness of diagnosis predicted changes in cognition and quality of life (QOL) 1 year later in older adults with normal cognition and dementia diagnoses.

Category:Health Professions

Relationships Between Cognitive Complaints and Quality of Life in Older Adults With Mild Cognitive Impairment, Mild Alzheimer Disease Dementia, and Normal Cognition

Posted: | S. D. Stites, K. Harkins, J. D. Rubright, J. Karlawish

Alzheimer Disease & Associated Disorders: October–December 2018 - Volume 32 - Issue 4 - p 276-283

 

The purpose of this study is to examine the relationship between self-reports of cognitive complaints and quality of life (QOL) in persons with varying degrees of cognitive impairment.

Category:Health Professions

Fit for Purpose and Modern Validity Theory in Clinical Outcomes Assessment

Posted: | M. C. Edwards, A. Slagle, J. D. Rubright, R. J. Wirth

Qual Life Res 27, 1711–1720 (2018)

 

The US Food and Drug Administration (FDA), as part of its regulatory mission, is charged with determining whether a clinical outcome assessment (COA) is “fit for purpose” when used in clinical trials to support drug approval and product labeling. This paper provides a review (and some commentary) on the current state of affairs in COA development/evaluation/use with a focus on one aspect: How do you know you are measuring the right thing? In the psychometric literature, this concept is referred to broadly as validity and has itself evolved over many years of research and application.

Category:Assessment-Oriented Research, General Measurement, Reliability/Validity